Gilead to expand access to remdesivir, its promising coronavirus treatment

Gilead Sciences Inc. will expand access to its experimental anti-coronavirus drug remdesivir to accelerate its emergency use for multiple severely ill patients.

The drugmaker said it’s switching to “expanded access” from a “compassionate use” program under which remdesivir was given to more than 1,000 Covid-19 patients.

“With expanded access, hospitals or physicians can apply for emergency use of remdesivir for multiple severely ill patients at a time,” Daniel O’Day, Gilead’s chairman and chief executive officer, said in an open letter sent by email Saturday. “While it will take some time to build a network of active sites, this approach will ultimately accelerate emergency access for more people.

A World Health Organization panel said in January that remdesivir was considered to be the most promising therapeutic candidate based on its broad antiviral spectrum, and existing data based on human and animal studies. The medication was developed initially for Ebola and studied in patients in Eastern Congo.

Multiple clinical trials are investigating the drug’s effects in Covid-19 patients in China and elsewhere. Initial results may be reported in the coming weeks, O’Day said.

If it is approved, the Foster City, California-based company “will work to ensure affordability and access so that remdesivir is available to patients with the greatest need,” he said.

“The urgency comes from knowing the desperate need among patients and the lack of any approved treatment,” O’Day said. “The responsibility is to ensure that remdesivir, an investigational medicine, is effective and safe before it is distributed for use worldwide.”

More coronavirus coverage from Fortune:

—Why Iceland’s approach to coronavirus testing may be better than America’s
—Everything you need to know about the coronavirus stimulus checks
—Glow sticks to surgical masks: Businesses pivot to tackle coronavirus shortages
—The world’s largest coronavirus lockdown is off to a rocky start
—The oil sector is quickly running out of storage for its unprecedented surplus
—The $2 trillion coronavirus stimulus package isn’t green, but it helps
—Listen to Leadership Next, a Fortune podcast examining the evolving role of CEO
—WATCH: World leaders and health experts on how to stop the spread of COVID-19

Subscribe to Outbreak, a daily newsletter roundup of stories on the coronavirus pandemic and its impact on global

Read more: https://fortune.com/2020/03/30/coronavirus-treatment-gilead-drug-remdesivir-expanded-access/

Trump adds 30 days to distancing guidelines as virus spreads

President Donald Trump is extending the voluntary national shutdown for a month as sickness and death from the coronavirus pandemic rise in the U.S.

The initial 15-day period of social distancing urged by the federal government expires Monday and Trump had expressed interest in relaxing the national guidelines at least in parts of the country less afflicted by the pandemic. But instead he decided to extend them through April 30, a tacit acknowledgment he’d been too optimistic. Many states and local governments have stiffer controls in place on mobility and gatherings.

Trump’s impulse to restore normalcy met a sober reality check Sunday from Dr. Anthony Fauci, the government’s top infectious disease expert, who said the U.S. could experience more than 100,000 deaths and millions of infections from the pandemic. Trump’s decision to extend the guidelines reflected a recognition that the struggle will take place over the longer haul.

The federal guidelines recommend against large group gatherings and urge older people and anyone with existing health problems to stay home. People are urged to work at home when possible and avoid restaurants, bars, non-essential travel and shopping trips.

The extension would leave the federal recommendations in place beyond Easter on April 12, by which time Trump had hoped the country and its economy could start to rev up again. Alarmed public-health officials said Easter was sure to be too soon.

The U.S. had more than 137,000 COVID-19 cases reported by late Sunday afternoon, with more than 2,400 deaths.

More coronavirus coverage from Fortune:

—Why Iceland’s approach to coronavirus testing may be better than America’s
—Everything you need to know about the coronavirus stimulus checks
—Glow sticks to surgical masks: Businesses pivot to tackle coronavirus shortages
—The world’s largest coronavirus lockdown is off to a rocky start
—The oil sector is quickly running out of storage for its unprecedented surplus
—The $2 trillion coronavirus stimulus package isn’t green, but it helps
—Listen to Leadership Next, a Fortune podcast examining the evolving role of CEO
—WATCH: World leaders and health experts on how to stop the spread of COVID-19

Subscribe to Outbreak, a daily newsletter roundup of stories on the coronavirus pandemic and its impact on global business. It’s free to get it in your inbox.

Read more: https://fortune.com/2020/03/29/coronavirus-social-distancing-april/

National Weather

Click on map for forecast

advertisement